EFS, embryonal Fyn-associated substrate

EFS, embryonal Fyn-associated substrate

• The longest protein isoform encoded by this gene contains an SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2013]

• Gene Synonyms (CAS3, CASS3, EFS1, EFS2, HEFS, SIN, embryonal Fyn-associated substrate, Cas scaffolding protein family member 3, signal transduction protein (SH3 containing),)
• NCBI Gene ID: 10278
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O43281
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

embryonal Fyn-associated substrate interacts with:

• coiled-coil domain containing 187
  glomulin, FKBP associated protein
  LIM homeobox 8
  myozenin 3
  neuroligin 3
  osteoclast stimulating factor 1
  PTK2 protein tyrosine kinase 2
  SH3 domain containing ring finger 2
  testis specific serine kinase 1B
  trafficking protein particle complex 6A
  ubiquitin associated and SH3 domain containing B
  zinc finger protein 417

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.