TBR1, T-box brain transcription factor 1

TBR1, T-box brain transcription factor 1

• This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015]

• Gene Synonyms (IDDAS, TBR-1, TES-56, T-box brain protein 1, T-box, brain 1, T-brain-1,)
• NCBI Gene ID: 10716
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q16650
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

T-box brain transcription factor 1 interacts with:

• methyltransferase like 3
  required for meiotic nuclear division 5 homolog B
  ring finger protein 123
  spindle apparatus coiled-coil protein 1
  TSPY like 2
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.