DMC1, DNA meiotic recombinase 1

DMC1, DNA meiotic recombinase 1

• This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

• Gene Synonyms (meiotic recombination protein DMC1/LIM15 homolog, DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination, disrupted meiotic cDNA1, yeast, homolog of, DMC1H, LIM15, dJ199H16.1,)
• NCBI Gene ID: 11144
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14565
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DNA meiotic recombinase 1 interacts with:

• chromosome 1 open reading frame 112
  COP1 E3 ubiquitin ligase
  DNA meiotic recombinase 1
  fidgetin like 1
  golgi reassembly stacking protein 2
  ligand of numb-protein X 1
  NGG1 interacting factor 3 like 1
  potassium channel tetramerization domain containing 17
  POTE ankyrin domain family member F
  RAD54 homolog B
  sirtuin 3
  small VCP interacting protein
  syndecan binding protein 2
  zinc finger protein 302

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.