HPS5, HPS5 biogenesis of lysosomal organelles complex 2 subunit 2

HPS5, HPS5 biogenesis of lysosomal organelles complex 2 subunit 2

• This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (Hermansky-Pudlak syndrome 5 protein, alpha integrin binding protein 63, ruby-eye protein 2 homolog, AIBP63, BLOC2S2,)
• NCBI Gene ID: 11234
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UPZ3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

HPS5 biogenesis of lysosomal organelles complex 2 subunit 2 interacts with:

• 3'-phosphoadenosine 5'-phosphosulfate synthase 1
  alanyl-tRNA synthetase domain containing 1
  cell division cycle 26
  centrosomal protein 135
  coiled-coil domain containing 22
  developmental pluripotency-associated 3
  differentially expressed in FDCP 8 homolog
  glutamine amidotransferase like class 1 domain containing 1
  histone deacetylase 6
  HPS6 biogenesis of lysosomal organelles complex 2 subunit 3
  kinesin family member C1
  lymphocyte protein tyrosine kinase
  mago homolog, exon junction complex core component
  proteasome (prosome, macropain) subunit, beta type 4
  protein phosphatase 2, regulatory subunit A, alpha
  Ras association (RalGDS/AF-6) domain family member 1
  regulator of chromosome condensation 1
  shugoshin 1
  structural maintenance of chromosomes 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.