THEM4, thioesterase superfamily member 4

THEM4, thioesterase superfamily member 4

• Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CTMP, acyl-coenzyme A thioesterase THEM4, C-terminal modulator protein, acyl-CoA thioesterase THEM4, carboxyl-terminal modulator protein,)
• NCBI Gene ID: 117145
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8K0C9
  UNIPROT ID#>>Q5T1C6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

thioesterase superfamily member 4 interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.