- Gene Overview
- Interaction Network
- Sequence Verification
NLRP13, NLR family pyrin domain containing 13
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This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
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Gene Synonyms (CLR19.7, NALP13, NOD14, PAN13, NACHT, LRR and PYD domains-containing protein 13, NACHT, LRR and PYD containing protein 13, NACHT, leucine rich repeat and PYD containing 13, nucleotide-binding oligomerization domain protein 14, nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 13,)
- NCBI Gene ID:
126204
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q86W25
UNIPROT ID#>>A0A0C4DGQ4
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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NLR family pyrin domain containing 13 interacts with:
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