RDH12, retinol dehydrogenase 12

RDH12, retinol dehydrogenase 12

• The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 13 and Retinitis Pigmentosa 53. [provided by RefSeq, Sep 2015]

• Gene Synonyms (LCA13, RP53, SDR7C2, retinol dehydrogenase 12, all-trans and 9-cis retinol dehydrogenase, retinol dehydrogenase 12 (all-trans/9-cis/11-cis), retinol dehydrogenase 12, all-trans and 9-cis, short chain dehydrogenase/reductase family 7C member 2,)
• NCBI Gene ID: 145226
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z613
  UNIPROT ID#>>Q96NR8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

retinol dehydrogenase 12 interacts with:

• actin related protein 2/3 complex inhibitor
  annexin A8 like 1
  zinc finger and BTB domain containing 8 opposite strand

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.