TMC8, transmembrane channel like 8

TMC8, transmembrane channel like 8

• Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008]

• Gene Synonyms (EV2, EVER2, EVIN2, transmembrane channel-like protein 8, epidermodysplasia verruciformis 2, epidermodysplasia verruciformis protein 2,)
• NCBI Gene ID: 147138
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R8N8
  UNIPROT ID#>>Q8IU68
  UNIPROT ID#>>B3KXZ8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transmembrane channel like 8 interacts with:

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