SASS6, SAS-6 centriolar assembly protein

SASS6, SAS-6 centriolar assembly protein

• The protein encoded by this gene is a central component of centrioles and is necessary for their duplication and function. Centrioles adopt a cartwheel-shaped structure, with the encoded protein forming the hub and spokes inside a microtubule cylinder. Defects in this gene are a cause of autosomal recessive primary microcephaly. [provided by RefSeq, Oct 2016]

• Gene Synonyms (spindle assembly abnormal protein 6 homolog, MCPH14, SAS-6, SAS6,)
• NCBI Gene ID: 163786
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q495U0
  UNIPROT ID#>>Q6UVJ0
  UNIPROT ID#>>B4DYM7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SAS-6 centriolar assembly protein interacts with:

• coiled-coil domain containing 138
  RANBP2 like and GRIP domain containing 1
  synaptonemal complex central element protein 3
  WASH complex subunit 2A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.