DOLK, dolichol kinase

DOLK, dolichol kinase

• The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.[provided by RefSeq, Apr 2010]

• Gene Synonyms (CDG1M, DK, DK1, SEC59, TMEM15, dolichol kinase, SEC59 homolog, dolichol kinase 1, transmembrane protein 15,)
• NCBI Gene ID: 22845
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UPQ8
  UNIPROT ID#>>A0A0S2Z597
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dolichol kinase interacts with:

• cAMP responsive element binding protein 3 like 1
  CD274 molecule
  chondrolectin
  ERGIC and golgi 3
  family with sequence similarity 209 member A
  fibronectin type III domain containing 9
  glutathione peroxidase 8 (putative)
  leucine rich repeat containing 4C
  polypeptide N-acetylgalactosaminyltransferase 8
  solute carrier family 2 member 12
  synaptoporin
  transmembrane protein 171
  transmembrane protein 45B
  transmembrane protein 80
  transmembrane protein adipocyte associated 1
  ubiquilin 1
  V-set immunoregulatory receptor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.