HEY1, hes related family bHLH transcription factor with YRPW motif 1

HEY1, hes related family bHLH transcription factor with YRPW motif 1

• This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

• Gene Synonyms (hairy/enhancer-of-split related with YRPW motif protein 1, HES-related repressor protein 1, HES-related repressor protein 2, basic helix-loop-helix protein OAF1, cardiovascular helix-loop-helix factor 2, class B basic helix-loop-helix protein 31, hairy and enhancer of split-related protein 1, hairy-related transcription factor 1, hairy/enhancer-of-split related with YRPW motif 1, BHLHb31, CHF2, HERP2, HESR1, HRT-1, NERP2, OAF1, hHRT1,)
• NCBI Gene ID: 23462
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DEI9
  UNIPROT ID#>>Q9Y5J3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

hes related family bHLH transcription factor with YRPW motif 1 interacts with:

• baculoviral IAP repeat containing 6
  centrosomal protein 192
  coiled-coil domain containing 124
  coiled-coil domain containing 78
  coiled-coil domain containing 88A
  CREB/ATF bZIP transcription factor
  derlin 2
  F-box and WD repeat domain containing 7
  F-box protein 45
  hes related family bHLH transcription factor with YRPW motif 1
  hes related family bHLH transcription factor with YRPW motif 2
  heterogeneous nuclear ribonucleoprotein L like
  keratin associated protein 6-2
  MIS18 binding protein 1
  pleckstrin homology domain containing B2
  protein kinase D2
  ribosomal protein L22 like 1
  synoviolin 1
  tankyrase 1 binding protein 1
  terminal nucleotidyltransferase 5D
  translation machinery associated 7 homolog
  tubulin alpha 3d
  tubulin beta class I
  YLP motif containing 1
  YTH N6-methyladenosine RNA binding protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.