ARL2BP, ADP ribosylation factor like GTPase 2 binding protein

ARL2BP, ADP ribosylation factor like GTPase 2 binding protein

• ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ADP-ribosylation factor-like protein 2-binding protein, ADP-ribosylation factor like 2 binding protein, ARF-like 2-binding protein, ARL2-binding protein, Arf-like 2 binding protein BART1, binder of ARF2 protein 1, binder of Arl Two, binder of Arl2, retinitis pigmentosa 66 (autosomal recessive), BART, BART1, RP66,)
• NCBI Gene ID: 23568
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R6U9
  UNIPROT ID#>>Q9Y2Y0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ADP ribosylation factor like GTPase 2 binding protein interacts with:

• cilia and flagella associated protein 20
  fibronectin type III and SPRY domain containing 1
  PNKD metallo-beta-lactamase domain containing

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