EBF3, EBF transcription factor 3

EBF3, EBF transcription factor 3

• This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma. [provided by RefSeq, Sep 2011]

• Gene Synonyms (transcription factor COE3, early B cell factor 3, olf-1/EBF-like 2, COE3, EBF-3, HADDS, O/E-2, OE-2,)
• NCBI Gene ID: 253738
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H4W6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EBF transcription factor 3 interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.