REXO2, RNA exonuclease 2

REXO2, RNA exonuclease 2

• This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]

• Gene Synonyms (oligoribonuclease, mitochondrial, REX2, RNA exonuclease 2 homolog, RNA exonuclease 2 homolog, small fragment nuclease, CGI-114, REX2, RFN, SFN,)
• NCBI Gene ID: 25996
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y3B8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RNA exonuclease 2 interacts with:

• abhydrolase domain containing 10, depalmitoylase
  cutA divalent cation tolerance homolog
  DnaJ heat shock protein family (Hsp40) member C5
  HtrA serine peptidase 2
  LEO1 homolog, Paf1/RNA polymerase II complex component
  mitotic spindle organizing protein 1
  NFU1 iron-sulfur cluster scaffold
  selenocysteine lyase
  thioredoxin domain containing 17

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.