SETBP1, SET binding protein 1

SETBP1, SET binding protein 1

• This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

• Gene Synonyms (SET-binding protein, MRD29, SEB,)
• NCBI Gene ID: 26040
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6X0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SET binding protein 1 interacts with:

• DENN domain containing 11
  pleckstrin homology and FYVE domain containing 2
  SET binding protein 1
  SPANX family member A2
  SPANX family member C
  SPANX family member D
  sperm protein associated with the nucleus, X-linked, family member A1
  X antigen family member 1B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.