C1GALT1C1, C1GALT1 specific chaperone 1

C1GALT1C1, C1GALT1 specific chaperone 1

• This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2009]

• Gene Synonyms (C1GALT1-specific chaperone 1, C38H2-like protein 1, beta 1,3-galactosyltransferase 2, core 1 beta1,3-galactosyltransferase 2, core 1 beta3-Gal-T2, core 1 beta3-galactosyltransferase-specific molecular chaperone, C1GALT2, C38H2-L1, COSMC, HSPC067, MST143, TNPS,)
• NCBI Gene ID: 29071
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96EU7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

C1GALT1 specific chaperone 1 interacts with:

• 2-oxoglutarate and iron dependent oxygenase domain containing 3
  5-hydroxytryptamine receptor 3C
  ADP dependent glucokinase
  core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
  potassium two pore domain channel subfamily K member 16
  solute carrier family 39 member 5
  solute carrier family 39 member 8
  zinc activated ion channel

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.