VSX1, visual system homeobox 1

VSX1, visual system homeobox 1

• The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• Gene Synonyms (visual system homeobox 1, homeodomain protein RINX, retinal inner nuclear layer homeobox protein, transcription factor VSX1, visual system homeobox 1 homolog, CHX10-like, CAASDS, KTCN, KTCN1, PPCD, PPCD1, PPD, RINX,)
• NCBI Gene ID: 30813
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NZR4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

visual system homeobox 1 interacts with:

• ubiquitin specific peptidase 12
  WD repeat domain 20

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.