KCNIP3, potassium voltage-gated channel interacting protein 3

KCNIP3, potassium voltage-gated channel interacting protein 3

• This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

• Gene Synonyms (calsenilin, A-type potassium channel modulatory protein 3, DRE-antagonist modulator, Kv channel interacting protein 3, calsenilin, calsenilin, presenilin-binding protein, EF hand transcription factor, kv channel-interacting protein 3, potassium channel interacting protein 3, CSEN, DREAM, KCHIP3,)
• NCBI Gene ID: 30818
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y2W7
  UNIPROT ID#>>A0A024RE22
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium voltage-gated channel interacting protein 3 interacts with:

• C1q and TNF related 2
  CD177 molecule
  golgin A7
  mitochondrial antiviral signaling protein
  potassium voltage-gated channel interacting protein 3
  pterin-4 alpha-carbinolamine dehydratase 2
  zymogen granule protein 16

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.