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HTR2A, 5-hydroxytryptamine receptor 2A

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HTR2A, 5-hydroxytryptamine receptor 2A

  • This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

  • Gene Synonyms (5-hydroxytryptamine receptor 2A, 5-HT2 receptor, 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled, serotonin 5-HT-2A receptor, 5-HT2A, HTR2,)
  • NCBI Gene ID: 3356
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>P28223
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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