STING1, stimulator of interferon response cGAMP interactor 1

STING1, stimulator of interferon response cGAMP interactor 1

• This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

• Gene Synonyms (ERIS, MITA, MPYS, NET23, SAVI, STING, STING-beta, TMEM173, hMITA, hSTING, stimulator of interferon genes protein, N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner, endoplasmic reticulum IFN stimulator, endoplasmic reticulum interferon stimulator, mitochondrial mediator of IRF3 activation, stimulator of interferon protein, transmembrane protein 173,)
• NCBI Gene ID: 340061
• Species: Homo sapiens (Human)
• UNIPROT ID#>>V5V0K2
  UNIPROT ID#>>Q86WV6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

stimulator of interferon response cGAMP interactor 1 interacts with:

• small integral membrane protein 1 (Vel blood group)
  stimulator of interferon response cGAMP interactor 1
  ubiquitin specific peptidase 50

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