SMARCAL1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1

SMARCAL1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1

• The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. [provided by RefSeq, Jul 2008]

• Gene Synonyms (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, ATP-driven annealing helicase, HepA-related protein, SMARCA-like protein 1, sucrose nonfermenting protein 2-like 1, HARP, HHARP,)
• NCBI Gene ID: 50485
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NZC9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 interacts with:

• antizyme inhibitor 2
  primase and DNA directed polymerase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.