FOXP3, forkhead box P3

FOXP3, forkhead box P3

• The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (forkhead box protein P3, FOXP3delta7, immune dysregulation, polyendocrinopathy, enteropathy, X-linked, immunodeficiency, polyendocrinopathy, enteropathy, X-linked, scurfin, AIID, DIETER, IPEX, JM2, PIDX, XPID,)
• NCBI Gene ID: 50943
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7ZLG1
  UNIPROT ID#>>Q9BZS1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

forkhead box P3 interacts with:

• BEN domain containing 3
  cell cycle and apoptosis regulator 2
  elongator acetyltransferase complex subunit 3
  epithelial splicing regulatory protein 2
  forkhead box P2
  forkhead box P4
  forkhead box R1
  histone deacetylase 7
  homeodomain interacting protein kinase 1
  IKAROS family zinc finger 4
  keratin associated protein 3-3
  keratin associated protein 6-2
  keratin associated protein 8-1
  lysine acetyltransferase 8
  NACC family member 2
  nemo like kinase
  nucleoporin 107
  nucleoporin 133
  nucleus accumbens associated 1
  proline rich 20A
  proline rich 20B
  proline rich 20C
  proline rich 20D
  proline rich 20E
  SET and MYND domain containing 2
  WRN helicase interacting protein 1
  zinc finger and BTB domain containing 34
  zinc finger and BTB domain containing 37
  zinc finger protein 326
  zinc finger RNA binding protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.