SAR1B, secretion associated Ras related GTPase 1B

SAR1B, secretion associated Ras related GTPase 1B

• The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]

• Gene Synonyms (GTP-binding protein SAR1b, 2310075M17Rik, GTP-binding protein B, GTP-binding protein Sara, SAR1 homolog B, SAR1a gene homolog 2, ANDD, CMRD, GTBPB, SARA2,)
• NCBI Gene ID: 51128
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y6B6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

secretion associated Ras related GTPase 1B interacts with:

• cell division cycle 73
  family with sequence similarity 177 member A1
  glycoprotein integral membrane 1
  OTU deubiquitinase with linear linkage specificity like
  phospholipid phosphatase related 2
  secretion associated Ras related GTPase 1A
  SRP receptor subunit beta
  transmembrane protein 14B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.