NME8, NME/NM23 family member 8

NME8, NME/NM23 family member 8

• This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009]

• Gene Synonyms (thioredoxin domain-containing protein 3, epididymis secretory protein Li 99, sperm-specific thioredoxin 2, spermatid-specific thioredoxin-2, thioredoxin domain containing 3 (spermatozoa), CILD6, HEL-S-99, NM23-H8, SPTRX2, TXNDC3, sptrx-2,)
• NCBI Gene ID: 51314
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N427
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NME/NM23 family member 8 interacts with:

• intraflagellar transport 20
  intraflagellar transport 57

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.