CHST15, carbohydrate sulfotransferase 15

CHST15, carbohydrate sulfotransferase 15

• Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

• Gene Synonyms (carbohydrate sulfotransferase 15, B cell RAG associated protein (GALNAC4S-6ST), B-cell RAG-associated gene protein, carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15, hBRAG, BRAG, GALNAC4S-6ST,)
• NCBI Gene ID: 51363
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7LFX5
  UNIPROT ID#>>B4DH74
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

carbohydrate sulfotransferase 15 interacts with:

• ILK associated serine/threonine phosphatase
  MORN repeat containing 5
  NADH:ubiquinone oxidoreductase complex assembly factor 2
  PHD finger protein 5A
  pleckstrin homology and RhoGEF domain containing G1
  RAB, member RAS oncogene family like 6
  Ras related GTP binding D
  solute carrier family 25 member 19
  solute carrier family 35 member E1
  tight junction associated protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.