DCDC2, doublecortin domain containing 2

DCDC2, doublecortin domain containing 2

• This gene encodes a doublecortin domain-containing family member. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. This family member is thought to function in neuronal migration where it may affect the signaling of primary cilia. Mutations in this gene have been associated with reading disability (RD) type 2, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2013]

• Gene Synonyms (doublecortin domain-containing protein 2, DCDC2A, DFNB66, NPHP19, NSC, RU2, RU2S,)
• NCBI Gene ID: 51473
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UHG0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

doublecortin domain containing 2 interacts with:

• centromere protein O
  dynein cytoplasmic 2 light intermediate chain 1
  family with sequence similarity 118 member A
  keratin associated protein 9-3
  LIM domain only 3
  MICAL like 2
  Morf4 family associated protein 1
  NGG1 interacting factor 3 like 1
  solute carrier family 38 member 2
  toll interacting protein
  UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.