NCKIPSD, NCK interacting protein with SH3 domain

NCKIPSD, NCK interacting protein with SH3 domain

• The protein encoded by this gene contains a nuclear localization signal. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation This protein is involved in the formation and maintenance of dendritic spines, and modulates synaptic activity in neurons. The gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2019]

• Gene Synonyms (NCK-interacting protein with SH3 domain, 54 kDa VacA-interacting protein, 54 kDa vimentin-interacting protein, 90 kDa SH3 protein interacting with Nck, SH3 adapter protein SPIN90, SH3 protein interacting with Nck, 90 kDa, WASP-interacting SH3-domain protein, dia interacting protein, dia-interacting protein 1, diaphanous protein interacting protein, wiskott-Aldrich syndrome protein-interacting protein, AF3P21, DIP, DIP1, ORF1, SPIN90, VIP54, WASLBP, WISH,)
• NCBI Gene ID: 51517
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NZQ3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NCK interacting protein with SH3 domain interacts with:

• centrobin, centriole duplication and spindle assembly protein
  coiled-coil domain containing 187
  copine 2
  diaphanous related formin 3
  DMRT like family B with proline rich C-terminal 1
  enkurin domain containing 1
  epidermal growth factor receptor pathway substrate 15 like 1
  FCH and double SH3 domains 1
  gem nuclear organelle associated protein 6
  gem nuclear organelle associated protein 8
  ligand dependent nuclear receptor interacting factor 1
  mediator complex subunit 25
  nuclear receptor interacting protein 3
  programmed cell death 2 like
  psoriasis susceptibility 1 candidate 2
  Ras association (RalGDS/AF-6) domain family member 1
  retinol binding protein 7
  RNA binding motif protein 15
  RNA binding motif protein 22
  sorting nexin 33
  structural maintenance of chromosomes 6
  tRNA splicing endonuclease subunit 54
  zinc finger and BTB domain containing 47
  zinc finger C2HC-type containing 1C

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.