- Gene Overview
- Interaction Network
- Sequence Verification
IL23A, interleukin 23 subunit alpha
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This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]
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Gene Synonyms (interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23-A, IL-23p19, JKA3 induced upon T-cell activation, interleukin 23 p19 subunit, interleukin 23, alpha subunit p19, interleukin-23 subunit p19, interleukin-six, G-CSF related factor, IL-23, IL-23A, IL23P19, P19, SGRF,)
- NCBI Gene ID:
51561
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q9NPF7
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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interleukin 23 subunit alpha interacts with:
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