POLR3K, RNA polymerase III subunit K

POLR3K, RNA polymerase III subunit K

• This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.[provided by RefSeq, Jul 2010]

• Gene Synonyms (DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit K, DNA-directed RNA polymerases III 12.5 kDa polypeptide, RNA polymerase III 12.5 kDa subunit, RNA polymerase III subunit C10, RNA polymerase III subunit C11, RNA polymerase III subunit CII, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa, polymerase (RNA) III subunit K, C11, C11-RNP3, My010, RPC10, RPC11, RPC12.5,)
• NCBI Gene ID: 51728
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y2Y1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RNA polymerase III subunit K interacts with:

• centromere protein P
  MUS81 structure-specific endonuclease subunit
  PIH1 domain containing 1
  ret finger protein like 4B
  RNA polymerase III subunit B
  RNA polymerase III subunit E
  RNA polymerase III subunit GL
  RuvB-like protein 1
  tripartite motif containing 69

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.