BCL11A, BAF chromatin remodeling complex subunit BCL11A

BCL11A, BAF chromatin remodeling complex subunit BCL11A

• This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (B-cell lymphoma/leukemia 11A, B cell CLL/lymphoma 11A, B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2, BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1, BCL11A, BAF complex component, C2H2-type zinc finger protein, COUP-TF-interacting protein 1, ecotropic viral integration site 9 homolog, ecotropic viral integration site 9 protein homolog, zinc finger protein 856, BCL11A-L, BCL11A-S, BCL11A-XL, BCL11a-M, CTIP1, DILOS, EVI9, HBFQTL5, ZNF856,)
• NCBI Gene ID: 53335
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H165
  UNIPROT ID#>>D9YZV9
  UNIPROT ID#>>D6W5D9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BAF chromatin remodeling complex subunit BCL11A interacts with:

• BAF chromatin remodeling complex subunit BCL11A
  cell division cycle associated 3
  F-box protein 38
  germ cell-less 2, spermatogenesis associated
  methyl-CpG binding domain protein 3
  methyl-CpG binding domain protein 3 like 1
  NFAT activating protein with ITAM motif 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.