MTRF1L, mitochondrial translational release factor 1 like

MTRF1L, mitochondrial translational release factor 1 like

• The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG. This protein shares sequence similarity to bacterial release factors. Pseudogenes of this gene are found on chromosomes 4, 8, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

• Gene Synonyms (peptide chain release factor 1-like, mitochondrial, mitochondrial release factor 1 like, HMRF1L, MRF1L, mtRF1a,)
• NCBI Gene ID: 54516
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DMX1
  UNIPROT ID#>>Q9UGC7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mitochondrial translational release factor 1 like interacts with:

• mitochondrial rRNA methyltransferase 1
  tRNA methyltransferase 61B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.