TET2, tet methylcytosine dioxygenase 2

TET2, tet methylcytosine dioxygenase 2

• The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

• Gene Synonyms (methylcytosine dioxygenase TET2, probable methylcytosine dioxygenase TET2, tet oncogene family member 2, KIAA1546, MDS,)
• NCBI Gene ID: 54790
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A158SIU0
  UNIPROT ID#>>A0A024RDF7
  UNIPROT ID#>>Q6N021
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tet methylcytosine dioxygenase 2 interacts with:

• BPI fold containing family B member 1
  dermcidin
  egl-9 family hypoxia inducible factor 3
  myosin heavy chain 14
  ring finger protein 31
  tubulin beta class I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.