CDCA4, cell division cycle associated 4

CDCA4, cell division cycle associated 4

• This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1. [provided by RefSeq, May 2014]

• Gene Synonyms (cell division cycle-associated protein 4, hematopoietic progenitor protein, HEPP, SEI-3/HEPP,)
• NCBI Gene ID: 55038
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R6P3
  UNIPROT ID#>>Q9BXL8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cell division cycle associated 4 interacts with:

• 3-hydroxybutyrate dehydrogenase 2
  docking protein 5
  enkurin domain containing 1
  family with sequence similarity 222 member B
  fibronectin type III domain containing 11
  kelch like family member 42
  nicotinamide nucleotide adenylyltransferase 1
  par-6 family cell polarity regulator beta
  protein arginine methyltransferase 6
  protein phosphatase 2 regulatory subunit Bdelta
  suppressor of variegation 3-9 homolog 2
  yippee like 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.