IL17RB, interleukin 17 receptor B

IL17RB, interleukin 17 receptor B

• The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CRL4, EVI27, IL17BR, IL17RH1, interleukin-17 receptor B, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17RB, IL-17Rh1, cytokine receptor CRL4, cytokine receptor-like 4, interleukin 17 receptor homolog 1, interleukin-17B receptor,)
• NCBI Gene ID: 55540
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NRM6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interleukin 17 receptor B interacts with:

• adhesion molecule with Ig like domain 1
  CDGSH iron sulfur domain 2
  interleukin 25
  ring finger protein 149
  selenoprotein O
  solute carrier family 35 member F5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.