DCAF6, DDB1 and CUL4 associated factor 6

DCAF6, DDB1 and CUL4 associated factor 6

• The protein encoded by this gene is a ligand-dependent coactivator of nuclear receptors, including nuclear receptor subfamily 3 group C member 1 (NR3C1), glucocorticoid receptor (GR), and androgen receptor (AR). The encoded protein and DNA damage binding protein 2 (DDB2) may act as tumor promoters and tumor suppressors, respectively, by regulating the level of androgen receptor in prostate tissues. In addition, this protein can act with glucocorticoid receptor to promote human papillomavirus gene expression. [provided by RefSeq, Mar 2017]

• Gene Synonyms (1200006M05Rik, ARCAP, IQWD1, MSTP055, NRIP, PC326, DDB1- and CUL4-associated factor 6, IQ motif and WD repeat-containing protein 1, IQ motif and WD repeats 1, androgen receptor complex-associated protein, nuclear receptor interaction protein,)
• NCBI Gene ID: 55827
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q58WW2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DDB1 and CUL4 associated factor 6 interacts with:

• C1q and TNF related 2
  calneuron 1
  chromobox 2
  chromosome 10 open reading frame 88
  DDB1 and CUL4 associated factor 6
  DET1 and DDB1 associated 1
  tripartite motif containing 55
  tripartite motif containing 63

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.