ANKS1B, ankyrin repeat and sterile alpha motif domain containing 1B

ANKS1B, ankyrin repeat and sterile alpha motif domain containing 1B

• This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. [provided by RefSeq, Aug 2011]

• Gene Synonyms (AIDA, AIDA-1, ANKS2, EB-1, EB1, cajalin-2, ankyrin repeat and sterile alpha motif domain-containing protein 1B, E2a-Pbx1-associated protein, amyloid-beta precursor protein intracellular domain associated protein 1, cajalin 2,)
• NCBI Gene ID: 56899
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B1VKB5
  UNIPROT ID#>>Q6V0K8
  UNIPROT ID#>>Q7Z6G8
  UNIPROT ID#>>B7Z9I9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ankyrin repeat and sterile alpha motif domain containing 1B interacts with:

• Cas scaffold protein family member 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.