PMEPA1, prostate transmembrane protein, androgen induced 1

PMEPA1, prostate transmembrane protein, androgen induced 1

• This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

• Gene Synonyms (STAG1, TMEPAI, protein TMEPAI, solid tumor-associated 1 protein, transmembrane, prostate androgen induced RNA,)
• NCBI Gene ID: 56937
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5JY37
  UNIPROT ID#>>Q969W9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

prostate transmembrane protein, androgen induced 1 interacts with:

• dynactin subunit 5
  OTU deubiquitinase, ubiquitin aldehyde binding 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.