CPA6, carboxypeptidase A6

CPA6, carboxypeptidase A6

• The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome. [provided by RefSeq, May 2016]

• Gene Synonyms (CPAH, ETL5, FEB11, carboxypeptidase A6, carboxypeptidase B,)
• NCBI Gene ID: 57094
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N4T0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

carboxypeptidase A6 interacts with:

• APC membrane recruitment protein 1
  F-box protein 15
  fucosyltransferase 11
  HECT domain E3 ubiquitin protein ligase 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.