ARHGAP21, Rho GTPase activating protein 21

ARHGAP21, Rho GTPase activating protein 21

• ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (ARHGAP10, rho GTPase-activating protein 21, Rho-GTPase activating protein 10, rho GTPase-activating protein 10, rho-type GTPase-activating protein 21,)
• NCBI Gene ID: 57584
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5T5U3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Rho GTPase activating protein 21 interacts with:

• calmodulin-like 3
  centromere protein E
  centrosomal protein 120
  centrosomal protein 128
  egl-9 family hypoxia inducible factor 3
  filamin, beta
  myosin XIX
  myosin XVIIIA
  myosin, heavy polypeptide 10, non-muscle
  spindle and centriole associated protein 1
  suppressor APC domain containing 1
  TNFAIP3 interacting protein 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.