MRTFA, myocardin related transcription factor A

MRTFA, myocardin related transcription factor A

• The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

• Gene Synonyms (BSAC, MAL, MKL, MKL1, MRTF-A, myocardin-related transcription factor A, MKL/myocardin-like protein 1, basic, SAP and coiled-coil domain, megakaryoblastic leukemia (translocation) 1, megakaryoblastic leukemia 1 protein, megakaryocytic acute leukemia protein,)
• NCBI Gene ID: 57591
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A4FUJ8
  UNIPROT ID#>>W0Z7M9
  UNIPROT ID#>>B0QY83
  UNIPROT ID#>>E7ER32
  UNIPROT ID#>>Q969V6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

myocardin related transcription factor A interacts with:

• centrosomal protein 19
  centrosomal protein 63
  lebercilin LCA5
  myocardin
  myocardin related transcription factor A
  tectonic family member 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.