MYH7B, myosin heavy chain 7B

MYH7B, myosin heavy chain 7B

• The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined. [provided by RefSeq, Mar 2010]

• Gene Synonyms (MHC14, MYH14, myosin-7B, U937-associated antigen, antigen MLAA-21, myosin heavy chain 7B, cardiac muscle beta isoform, myosin, heavy chain 7B, cardiac muscle, beta, myosin, heavy polypeptide 7B, cardiac muscle, beta, slow A MYH14,)
• NCBI Gene ID: 57644
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A7E2Y1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

myosin heavy chain 7B interacts with:

• COP9 signalosome subunit 7B
  DNA polymerase delta interacting protein 3
  leucine rich repeat and coiled-coil centrosomal protein 1
  PGAM family member 5, mitochondrial serine/threonine protein phosphatase
  SET and MYND domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.