RHOU, ras homolog family member U

RHOU, ras homolog family member U

• This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.[provided by RefSeq, Mar 2011]

• Gene Synonyms (rho-related GTP-binding protein RhoU, 2310026M05Rik, CDC42-like GTPase 1, GTP-binding protein SB128, GTP-binding protein like 1, Ryu GTPase, ras homolog gene family, member U, ras-like gene family member U, rho GTPase-like protein ARHU, wnt-1 responsive Cdc42 homolog 1, ARHU, CDC42L1, G28K, WRCH1, hG28K,)
• NCBI Gene ID: 58480
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R3Q7
  UNIPROT ID#>>Q7L0Q8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ras homolog family member U interacts with:

• 3-oxoacid CoA-transferase 2
  adrenomedullin 2
  ALG13 UDP-N-acetylglucosaminyltransferase subunit
  BCL2 interacting protein like
  BMP/retinoic acid inducible neural specific 3
  cilia and flagella associated protein 100
  C-type lectin domain containing 7A
  cyclin dependent kinase like 4
  dishevelled binding antagonist of beta catenin 2
  family with sequence similarity 110 member B
  FCH and mu domain containing endocytic adaptor 2
  histidine triad nucleotide binding protein 3
  hydroxysteroid 17-beta dehydrogenase 13
  INSM transcriptional repressor 2
  interleukin 17F
  junctional adhesion molecule 3
  kidney associated antigen 1
  layilin
  polypeptide N-acetylgalactosaminyltransferase like 5
  queuine tRNA-ribosyltransferase catalytic subunit 1
  RAB40A, member RAS oncogene family
  Rho guanine nucleotide exchange factor 25
  ribosomal biogenesis factor
  scavenger receptor cysteine rich family member with 4 domains
  SEC14 like lipid binding 4
  transmembrane protein 106A
  transmembrane protein 169
  transmembrane protein 255B
  tripartite motif containing 59
  zinc finger AN1-type containing 2B
  zinc finger protein 569
  zinc finger protein 625
  zinc finger protein 747

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.