TNMD, tenomodulin

TNMD, tenomodulin

• This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009]

• Gene Synonyms (tenomodulin, BRICHOS domain containing 4, chondromodulin-1-like protein, chondromodulin-I-like protein, chondromodulin-IB, hChM1L, hTeM, myodulin, tendin, BRICD4, CHM1L, TEM,)
• NCBI Gene ID: 64102
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H2S6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tenomodulin interacts with:

• ADP ribosylation factor like GTPase 13B
  cAMP responsive element binding protein 3 like 1
  family with sequence similarity 209 member A
  gamma-glutamyltransferase 6
  killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3
  transmembrane protein 106A
  transmembrane protein 79

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.