MPP5, membrane palmitoylated protein 5

MPP5, membrane palmitoylated protein 5

• This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

• Gene Synonyms (MAGUK p55 subfamily member 5, membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5), protein associated with Lin-7 1, protein associated with lin seven 1, stardust, PALS1,)
• NCBI Gene ID: 64398
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q658X5
  UNIPROT ID#>>Q8N3R9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

membrane palmitoylated protein 5 interacts with:

• angiomotin
  angiomotin like 1
  basic helix-loop-helix family member b9
  centrosomal protein 128
  crumbs cell polarity complex component 3
  par-6 family cell polarity regulator beta
  ring finger protein 19B
  SLIT-ROBO Rho GTPase activating protein 2B
  suppressor of cytokine signaling 4
  syntaxin binding protein 4
  TNFAIP3 interacting protein 2
  WW domain containing transcription regulator 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.