WNK1, WNK lysine deficient protein kinase 1

WNK1, WNK lysine deficient protein kinase 1

• This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010]

• Gene Synonyms (serine/threonine-protein kinase WNK1, WNK lysine deficient protein kinase 1 isoform, erythrocyte 65 kDa protein, prostate-derived sterile 20-like kinase, protein kinase with no lysine 1, protein phosphatase 1, regulatory subunit 167, serine/threonine-protein kinase WNK1 1, serine/threonine-protein kinase WNK1 2, HSAN2, HSN2, KDP, PPP1R167, PRKWNK1, PSK, p65,)
• NCBI Gene ID: 65125
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A5D8Z4
  UNIPROT ID#>>F5GWT4
  UNIPROT ID#>>Q9H4A3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

WNK lysine deficient protein kinase 1 interacts with:

• alanyl-tRNA synthetase domain containing 1
  GLIS family zinc finger 2
  methyltransferase like 6
  spermatogenesis associated 1
  synaptotagmin 2
  TSC22 domain family member 4
  WNK lysine deficient protein kinase 1
  WNK lysine deficient protein kinase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.