- Gene Overview
- Interaction Network
- Sequence Verification
SFTPA1, surfactant protein A1
-
This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
-
Gene Synonyms (COLEC4, PSAP, PSP-A, PSPA, SFTP1, SFTPA1B, SP-A, SP-A1, SP-A1 beta, SP-A1 delta, SP-A1 epsilon, SP-A1 gamma, SPA, SPA1, pulmonary surfactant-associated protein A1, 35 kDa pulmonary surfactant-associated protein, alveolar proteinosis protein, collectin-4, surfactant protein A1B, surfactant, pulmonary-associated protein A1A, surfactant, pulmonary-associated protein A1B,)
- NCBI Gene ID:
653509
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>A0A024QZP2
UNIPROT ID#>>Q8IWL2
UNIPROT ID#>>B4DNP6
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
surfactant protein A1 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|