- Gene Overview
- Interaction Network
- Sequence Verification
ALG12, ALG12 alpha-1,6-mannosyltransferase
-
This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq, Jul 2008]
-
Gene Synonyms (dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase, asparagine-linked glycosylation 12 homolog (S. cerevisiae, alpha-1,6-mannosyltransferase), asparagine-linked glycosylation 12 homolog (yeast, alpha-1,6-mannosyltransferase), asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog, asparagine-linked glycosylation protein 12 homolog, dol-P-Man dependent alpha-1,6-mannosyltransferase, dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase, dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase, dolichyl-P-mannose:Man-7-GlcNAc-2-PP-dolichyl-alpha-6-mannosyltransferase, mannosyltransferase ALG12 homolog, membrane protein SB87, CDG1G, ECM39, PP14673, hALG12,)
- NCBI Gene ID:
79087
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>Q9BV10
UNIPROT ID#>>A0A024R4V6
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
ALG12 alpha-1,6-mannosyltransferase interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|