NHEJ1, non-homologous end joining factor 1

NHEJ1, non-homologous end joining factor 1

• Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008]

• Gene Synonyms (non-homologous end-joining factor 1, XRCC4-like factor, nonhomologous end-joining factor 1, protein cernunnos, XLF,)
• NCBI Gene ID: 79840
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9H9Q4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

non-homologous end joining factor 1 interacts with:

• non-homologous end joining factor 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.