EFHD1, EF-hand domain family member D1

EFHD1, EF-hand domain family member D1

• This gene encodes a member of the EF-hand super family of calcium binding proteins, which are involved in a variety of cellular processes including mitosis, synaptic transmission, and cytoskeletal rearrangement. The protein encoded by this gene is composed of an N-terminal disordered region, proline-rich elements, two EF-hands, and a C-terminal coiled-coil domain. This protein has been shown to associate with the mitochondrial inner membrane, and in HeLa cells, acts as a novel mitochondrial calcium ion sensor for mitochondrial flash activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

• Gene Synonyms (EF-hand domain-containing protein D1, EF-hand domain-containing protein 1, swiprosin-2, MST133, MSTP133, PP3051, SWS2,)
• NCBI Gene ID: 80303
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BUP0
  UNIPROT ID#>>Q8WYH2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EF-hand domain family member D1 interacts with:

• coiled-coil-helix-coiled-coil-helix domain containing 10
  complexin 4
  forkhead box P2
  peptidylprolyl isomerase A like 4G

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.