KDM5C, lysine demethylase 5C

KDM5C, lysine demethylase 5C

• This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

• Gene Synonyms (lysine-specific demethylase 5C, JmjC domain-containing protein SMCX, Jumonji, AT rich interactive domain 1C (RBP2-like), Jumonji/ARID domain-containing protein 1C, Smcx homolog, X chromosome, Smcy homolog, X-linked, [histone H3]-trimethyl-L-lysine(4) demethylase 5C, histone demethylase JARID1C, lysine (K)-specific demethylase 5C, DXS1272E, JARID1C, MRX13, MRXJ, MRXSCJ, MRXSJ, SMCX, XE169,)
• NCBI Gene ID: 8242
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P41229
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysine demethylase 5C interacts with:

• bromodomain containing 4
  centromere protein K
  chromobox 3
  differentially expressed in FDCP 8 homolog
  forkhead box J2
  H3 clustered histone 15
  histone deacetylase 6
  immediate early response 2
  IQ motif containing N
  LIM homeobox 6
  LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
  lysine demethylase 5C
  MAX dimerization protein MGA
  methyl-CpG binding domain protein 2
  nuclear receptor corepressor 1
  nuclear RNA export factor 1
  olfactomedin 2
  PITH domain containing 1
  polybromo 1
  Rho GTPase activating protein 25
  Scm polycomb group protein like 4
  slingshot protein phosphatase 3
  solute carrier family 25 member 22
  spermatogenesis associated 1
  thiamine triphosphatase
  TOX high mobility group box family member 4
  tripartite motif containing 35
  TSPY like 2
  vir like m6A methyltransferase associated
  VPS41 subunit of HOPS complex
  zinc finger MYND-type containing 8
  zinc finger protein 532
  zinc finger protein 592
  zinc finger protein 687

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.